Serpinin

• Catalog Number: orb2563719
• Category: Small Molecules
• Description: Serpinin, an agonist of the protease inhibitor Nexin-1 (PN-1), upregulates PN-1 expression via the cAMP-PKA-Sp1 signaling pathway, facilitating granule biogenesis in endocrine cells. It is employed in research on secretory function regulation [1]. Serpinin selectively targets β-adrenergic receptors, particularly interacting with β1-adrenergic receptors to activate the AC-cAMP-PKA pathway, thereby regulating myocardial systolic and diastolic function. Additionally, pGlu-serpinin upregulates Bcl2 mRNA transcription and provides neuroprotective effects [2].
• Purity: 98.00%
• MW: 2891.14
• CAS Number: 1383743-23-4
• Formula: C₁₂₅H₂₀₄N₃₂O₄₆
• SMILES: [C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]2CCCN2)CCC(O)=O)=O)CC(O)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CO)=O)CC(C)C)=O)CO)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCCCN)=O)C(C)C)=O)C)=O
• Storage: -20°C
• Note: For research use only