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Catalog Number | orb1961158 |
---|---|
Category | Small Molecules |
Description | SEMA4C Protein, Mouse, Recombinant (hFc) |
Purity | 98.00% |
MW | 115-125 KDa, reducing conditions |
Biological Activity | Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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