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Catalog Number | orb668900 |
---|---|
Category | Antibodies |
Description | SARS-CoV-2 Spike RBD Neutralizing Antibody |
Species/Host | Human |
Clonality | Recombinant |
Reactivity | Mouse |
Isotype | Human IgG1 | Human Kappa |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
Target | Spike RBD |
Source | Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2) and Omicron (B.1.1.529). |
Expression System | HEK293 |
Endotoxins | 1.0 EU per μg |
Storage | -20°C |
Buffer/Preservatives | PBS, pH 7.4 |
Note | For research use only |
Application notes | This antibody can be paired with other Anti-SARS-CoV-2 Spike S1 antibodies to detect SARS-CoV-2 Spike S1 protein in sandwich ELISA or LFA assay. |
Expiration Date | 12 months from date of receipt. |
ELISA, WB | |
Human | |
Recombinant | |
Unconjugated |
Unconjugated | |
90% | |
101.9 kDa | |
SARS-CoV-2 S1 protein, Mouse IgG2a Fc Tag (orb640170) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). |
ELISA, WB | |
Mouse | |
Recombinant | |
Unconjugated |
ELISA, WB | |
Mouse | |
Recombinant | |
Unconjugated |
FC, NeA | |
Virus | |
Rabbit | |
Recombinant | |
Unconjugated |
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