RFX1 (C) Antibody, Rabbit Polyclonal

SKU: orb131896

Description

Rabbit polyclonal to RFX1. Regulatory factor X 1 (RFX1) is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX1 is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. RFX1 binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat required for expression of hepatitis B virus genes.

Research Area

Epigenetics

Images & Validation

• Tested Applications: ChIP, WB
• Dilution Range: WB:1:1000-1:3000
• Reactivity: Human
• Application Notes:
  WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human RFX1.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human RFX1
• Molecular Weight: 105
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti MHC class II regulatory factor RFX1 antibody, anti Enhancer factor C antibody, anti EF-C antibody, anti Regulatory factor X 1 antibody, anti RFX antibody, anti Transcription factor RFX1 antibody

Quick Database Links

UniProt

P22670