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Recombinant Human soluble Tumor Necrosis Factor-Related Apoptosis-inducing Ligand Receptor-2/TNFRSF10B
Catalog Number: orb1906299
| Catalog Number | orb1906299 |
|---|---|
| Category | Proteins |
| Description | Recombinant Human soluble Tumor Necrosis Factor-Related Apoptosis-inducing Ligand Receptor-2/TNFRSF10B |
| Form/Appearance | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Purity | > 97 % by SDS-PAGE and HPLC analyses. |
| MW | Approximately 14.8 kDa, a single non-glycosylated polypeptide chain containing 132 amino acids. |
| UniProt ID | O14763 |
| Protein Sequence | ESALITQQDL APQQRAAPQQ KRSSPSEGLC PPGHHISEDG RDCISCKYGQ DYSTHWNDLL FCLRCTRCDS GEVELSPCTT TRNTVCQCEE GTFREEDSPE MCRKCRTGCP RGMVKVGDCT PWSDIECVHK ES |
| Source | Escherichia coli |
| Expression System | Escherichia coli |
| Biological Activity | Fully biologically active when compared to standard. rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/mL) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed. |
| Endotoxins | Less than 1 EU/ug of rHusTRAIL-R2 as determined by LAL method. |
| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Alternative names | soluble TRAIL Receptor-2, DR5, TNFRSF10B, KILER, T Read more... |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
