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Catalog Number | orb2635625 |
---|---|
Category | Antibodies |
Description | This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. |
Clonality | Recombinant |
Species/Host | Rabbit |
Isotype | Rabbit IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | A portion of amino acids 437-450 from the human protein was used as the immunogen for the recombinant Beta Tubulin antibody. |
UniProt ID | Q13509 |
Tested applications | IHC-P |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml |
Application notes | Optimal dilution of the recombinant Beta Tubulin antibody should be determined by the researcher. |
Antibody Type | Primary Antibody |
Clone Number | TUBB3/7089R |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Hazard Information | This recombinant Beta Tubulin antibody is available for research use only. |
Note | For research use only |
IHC staining of FFPE human ovarian carcinoma tissue with recombinant Beta Tubulin antibody (clone TUBB3/7089R). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free recombinant Beta Tubulin antibody (clone TUBB3/7089R) as confirmation of integrity and purity.
IHC-P | |
Human | |
Rabbit | |
Recombinant | |
Unconjugated |