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Catalog Number | RCP9212 |
---|---|
Category | Proteins |
Description | Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumour cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence. |
Tag | N terminal containing a HIS tag |
Form/Appearance | Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH 6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol). |
Buffer/Preservatives | 1X Laemmli buffer |
Purity | > 95 %, by SDS-PAGE under reducing conditions |
Protein Length | Met1-Pro531 |
UniProt ID | P14618 |
MW | 62.31 kDa |
Application notes | ELISA, Western Blotting, etc. |
Expression System | E.coli |
Source | E.coli -derived human recombinant protein |
Storage | at -20 °C |
Alternative names | M2PK, PKM2, Pyruvate kinase 3 isoform 1 |
Note | For research use only |