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Catalog Number | RCP9197 |
---|---|
Category | Proteins |
Description | Integrin-linked kinase (ILK1) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 interacts with the cytoplasmic domains of integrin β1 and β3 subunits as well as several adaptors and signalling proteins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 has been reported to regulate a number of biological properties including anchorage-independent cell cycle progression, tumour cell invasion and apoptosis. Over-expression of ILK1 has been documented in a wide variety of human malignancies. |
Tag | N terminal containing a HIS tag |
Form/Appearance | Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH 6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol). |
Buffer/Preservatives | 1X Laemmli buffer |
Purity | > 95 %, by SDS-PAGE under reducing conditions |
Protein Length | Met1- Lys452 |
UniProt ID | Q13418 |
MW | 55.92 kDa |
Application notes | ELISA, Western Blotting, etc. |
Expression System | E.coli |
Source | E.coli -derived human recombinant protein |
Storage | at -20 °C |
Alternative names | ILK-1, ILK-2, 59 kDa serine/threonine-protein kina Read more... |
Note | For research use only |