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Catalog Number | RCP9233 |
---|---|
Category | Proteins |
Description | Cyclin-dependent kinase 4 combines with the protein cyclin D to form a protein complex that promotes the passage of cells through the G1 checkpoint in the cell growth cycle. This cellular activity is regulated by the protein p16 produced by p16INK4a. Normally, p16 controls cell growth by inhibiting the activity of the CDK4–cyclin D complex and stopping cells at the G1 checkpoint. |
Tag | N terminal containing a HIS tag |
Form/Appearance | Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH 6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol). |
Buffer/Preservatives | 1X Laemmli buffer |
Purity | > 95 %, by SDS-PAGE under reducing conditions |
Protein Length | Met1- Glu303 |
UniProt ID | P11802 |
MW | 37.47 kDa |
Application notes | ELISA, Western Blotting, etc. |
Expression System | E.coli |
Source | E.coli -derived human recombinant protein |
Storage | at -20 °C |
Alternative names | CDK4 |
Note | For research use only |