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Catalog Number | orb1958963 |
---|---|
Category | Proteins |
Description | PSMB6 subunit belongs to the 20S proteasomal subunit family, which plays an importance role in the antigen presentation by MHC class I molecular. Proteasome subunit beta type 6 (PSMB6) is a member of 20S proteasomal subunit family, which forms the proteolytic core of 26S proteasome. PSMB6 knockdown decreased cellular viability under DM treatment. PSMB6 is associated with DM resistance in mosquitoes and that proteasome inhibitors such as MG-132 or bortezomib are suitable for use as a DM synergist for vector control. |
Tag | N-His |
Purity | 98.00% |
UniProt ID | Q60692 |
MW | 24.2 kDa (predicted) |
Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Expression System | E. coli |
Biological Origin | Mouse |
Biological Activity | PSMB6 subunit belongs to the 20S proteasomal subunit family, which plays an importance role in the antigen presentation by MHC class I molecular. Proteasome subunit beta type 6 (PSMB6) is a member of 20S proteasomal subunit family, which forms the proteolytic core of 26S proteasome. PSMB6 knockdown decreased cellular viability under DM treatment. PSMB6 is associated with DM resistance in mosquitoes and that proteasome inhibitors such as MG-132 or bortezomib are suitable for use as a DM synergist for vector control. |
Expression Region | A DNA sequence encoding the mouse Psmb6 (NP_032972.3) (Thr34-Pro238) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: Met |
Storage | -20°C |
Note | For research use only |