PSAP/Prosaposin Protein, Rat, Recombinant (His)

• Catalog Number: orb1959348
• Category: Proteins
• Description: Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previously localized to 10q21-->q22 by isotopic in situ hybridization using a human prosaposin cDNA as a probe. Using fluorescence in situ hybridization with a mouse genomic prosaposin fragment as probe, confirms the localization of PSAP and precisely maps it to band 10q22.1. PSAP/Prosaposin Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61 kDa and the accession number is A6K3X0.
• Tag: C-His
• Purity: 98.00%
• UniProt ID: A6K3X0
• MW: 61 kDa (predicted)
• Application notes: A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
• Expression System: HEK293 Cells
• Biological Origin: Rat
• Biological Activity: Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previously localized to 10q21-->q22 by isotopic in situ hybridization using a human prosaposin cDNA as a probe. Using fluorescence in situ hybridization with a mouse genomic prosaposin fragment as probe, confirms the localization of PSAP and precisely maps it to band 10q22.1. PSAP/Prosaposin Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61 kDa and the accession number is A6K3X0.
• Expression Region: A DNA sequence encoding the rat Psap (NP_037145.2) (Met1-Asn554) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ser 17
• Storage: -20°C
• Note: For research use only