Recombinant Mouse Amyloid beta A4 protein (App)

SKU: orb1881783

Description

This Recombinant Mouse Amyloid beta A4 protein (App) spans the amino acid sequence from region 18-770aa. Purity: Greater than 95% as determined by SDS-PAGE.

Research Area

Neuroscience; Cell Biology

Images & Validation

• Application Notes:
  We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

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Key Properties

• Source: E.coli
• Biological Origin: Mus musculus (Mouse)
• Tag: C-terminal 6xHis-tagged
• Expression Region: 18-770aa
• Protein Length: Full Length of Mature Protein
• MW: 91.8 kDa
• Purity: Greater than 95% as determined by SDS-PAGE.
• Protein Sequence: LEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEEEADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVSTQSLLKTTSEPLPQDPDKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN

Storage & Handling

• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
• Form/Appearance: Liquid or Lyophilized powder
• Buffer/Preservatives: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ABPP;APP;Alzheimer disease amyloid A4 protein homolog;Alzheimer disease amyloid protein;Amyloid precursor protein;Amyloid-beta (A4;Amyloid-beta A4 protein;Amyloidogenic glycoprotein;AG;S-APP-alpha;S-APP-beta;APP-C99;Beta-secretase C-terminal fragment;Beta-CTF;Abeta42;Beta-APP42;Abeta40;Beta-APP40;Alpha-secretase C-terminal fragment;Alpha-CTF;42;40;APP-C59;Amyloid intracellular domain 59;AID(59;Gamma-CTF(59;APP-C57;Amyloid intracellular domain 57;AID(57;Gamma-CTF(57;Amyloid intracellular domain 50;AID(50;Gamma-CTF(50

Quick Database Links

UniProt

P12023

Ou Chen et al. Modulating tumor-associated macrophages through APP-CD74 blockade with IL4R-exosomes synergizes with PD-1 inhibition in gastric cancer NPJ Precis Oncol, (2026)

PubMed: 41882095