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[Leu144,Arg147]-PLP (139-151)

SKU: orb2563666

Description

[Leu144,Arg147]-PLP (139-151) is a modified myelin proteolipid protein fragment that acts as a TCR antagonist, suppressing encephalitogenic Th1 clone activation in vitro and inhibiting experimental autoimmune encephalomyelitis (EAE) progression in vivo, making it a key tool for neuroimmunology and multiple sclerosis research.

Images & Validation

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Key Properties

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CAS Number188859-65-6
MW1467.71
FormulaC67H110N20O17
SMILESC(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)CCCCN)=O)CC(O)=O)(=O)[C@H]2N(C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)N)=O)CO)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CCC2

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

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No computed properties available.

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide