[Leu144]-PLP (139-151)

SKU: orb2563819

Description

L144-PLP(139-151) is a T cell receptor (TCR) antagonist peptide that selectively suppresses the activation of pathogenic encephalitogenic Th1 clones. It is a key research tool for studying TCR signaling and autoimmune mechanisms, such as multiple sclerosis, in both in vitro T cell assays and in vivo experimental autoimmune encephalomyelitis (EAE) models.

Key Properties

• CAS Number: 202462-61-1
• MW: 1448.67
• Formula: C₆₇H₁₀₅N₁₉O₁₇
• SMILES: C([C@H](CC1=CN=CN1)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)N)=O)CO)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)CCCCN)=O)CC(O)=O)=O)CCC3

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172638597