KYL peptide

SKU: orb1679452

Description

KYL peptide is a cell-permeable inhibitor of the EphA4 receptor (Kd = 0.8 μM) that blocks EphA4-ephrinA5 interactions. It demonstrates neuroprotective effects by preventing Aβ oligomer-induced synaptic toxicity and LTP blockade in hippocampal neurons, and it exhibits prolonged stability in cell culture media.

Research Area

Signal Transduction

Key Properties

• Target: Ephrin Receptor
• CAS Number: 676657-00-4
• MW: 1465.75
• Formula: C₇₄H₁₀₈N₁₄O₁₇
• SMILES: C([C@@H](C(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CO)=O)CO)=O)CC(C)C)=O)[C@H](C)C)=O)CCC1)NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](CCCCN)N)=O)=O)CC(C)C)=O)CCC2)CC4=CC=C(O)C=C4)=O)C=5C=6C(NC5)=CC=CC6

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

91691122