IGF-1R (Phospho-Tyr1165/Tyr1166) Rabbit Polyclonal Antibody

SKU: orb14812

Description

This is a rabbit polyclonal antibody targeting IGF-1R. It is unconjugated and suitable for use in IHC, WB applications. The antibody is reactive with human, mouse, rat samples. Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: IHC, WB
• Dilution Range: WB: 1:500 - 1:1000; IHC: 1：50 - 1：100
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide-KLH. Peptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y(p)-Y(p)-R-K) derived from Human IGF-1R
• Target: IGF-1R
• Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide.
• Concentration: 1.0mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Insulin-like growth factor I receptor; CD221; IGF1R; kinase IGF1R;

Quick Database Links

Gene Symbol

IGF-1R

UniProt

P08069

Marta Lopez-Cerda 1, Laura Lorenzo-Sanz 2, Victoria da Silva-Diz 2 3, Sandra Llop 4, Rosa M Penin 5, Josep Oriol Bermejo 6, Richard de Goeij-de Haas 7, Sander R Piersma 7, Thang V Pham 7, Connie R Jimenez 7, Juan Martin-Liberal 8, Purificación Muñoz IGF1R signaling induces epithelial-mesenchymal plasticity via ITGAV in cutaneous carcinoma J Exp Clin Cancer Res ., (2024)

PubMed: 39075581

Applications

IF

Reactivity

Mouse