Human ULBP4 Protein, His Tag

SKU: orb3245166

Description

ULBP4 (UL16-binding protein 4), also known as RAET1E (retinoic acid early transcript 1E), NKG2DL4 (NKG2D ligand 4) and LETAL (lymphocyte effector cell toxicity activating ligand), is a member of the ULBP/RAET1 family. This and ULBP-5/RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses.

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.3 kDa. The protein migrates as 33-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: HEK293
• Target: ULBP4
• Reactivity: Human
• Tag: C-10×His
• Expression Region: His 31 - Asp 225
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated
• MW: 24.3 kDa
• Purity: 90%

Storage & Handling

• Storage: -20°C to -70°C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
• Form/Appearance: Powder
• Buffer/Preservatives: PBS, pH 7.4
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ULBP4

RefSeq:Q8TD07