Human IL-17 RB Protein, His Tag

SKU: orb3245068

Description

IL17RB (EVI27, IL17Rh1) is a single pass transmembrane receptor which belongs to IL17R family of cytokine receptors. It was found to be expressed in liver, brain, testis and lungs. The ligand for IL17RB is IL17E, also known as IL25. The five IL-17 receptors (IL17RA-IL17RE) exhibit considerable sequence divergence between one another, but all appear to contain extracellular domains composed of fibronectin type-III (FnIII) domains, and cytoplasmic SEF/IL-17R (SEFIR) domains that show loose homology to Toll/IL-1R (TLR) domains.

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.2 kDa. The protein migrates as 45-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: HEK293
• Target: IL-17 RB
• Reactivity: Human
• Tag: C-10×His
• Expression Region: Arg 18 - Pro 292
• Endotoxins: 1.0 EU per μg
• Conjugation: Unconjugated
• MW: 32.2 kDa
• Purity: 95%

Storage & Handling

• Storage: -20°C to -70°C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
• Form/Appearance: Powder
• Buffer/Preservatives: PBS, pH 7.4
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

IL-17 RB

RefSeq:Q9NRM6