HSD3B1 Rabbit Polyclonal Antibody

SKU: orb5478

Description

HSD3B1 Rabbit Polyclonal Antibody

Research Area

Metabolism Research

Images & Validation

• Tested Applications: IF, IHC-Fr, IHC-P
• Dilution Range: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
• Reactivity: Mouse, Rat
• Predicted Reactivity: Bovine, Canine, Equine, Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human HSD3B1 (301-373/373aa)
• Target: HSD3B1
• Molecular Weight: 41 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

3BETAHSD; HSD3B; HSDB3; HSDB3A; SDR11E1; 3-beta-HSD I; D3Ertd383e; 3BHS1_HUMAN; HSD3B1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I (3-beta-HSD I); 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase; Steroid Delta-isomerase; Trophoblast antigen FDO161G; 3BH; 3BHS2_MOUSE; Hsd3b2; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II (3-beta-HSD II); 3BHS1_RAT; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; short chain dehydrogenase/reductase family 11E, member 1

Quick Database Links

Gene Symbol

HSD3B1

UniProt

P14060

Jin Zhou, Yanping Hou, Zhiyuan Zhang, Xiaoyu Xing, Xiangyu Zou, Liang Zhong, Hua Huang, Zhen Zhang, Jie Sun Conversion of human fibroblasts into functional Leydig-like cells by small molecules and a single factor Biochemical and Biophysical Research Communications, 516, 1 (2019)

PubMed: 31182281

Applications

IF

Reactivity

Human

Hua Huang, Xiangyu Zou, Liang Zhong, Yanping Hou, Jin Zhou, Zhiyuan Zhang, Xiaoyu Xing, Jie Sun CRISPR/dCas9‐mediated activation of multiple endogenous target genes directly converts human foreskin fibroblasts into Leydig‐like cells Journal of Cellular and Molecular Medicine, 23, 6072 (2019)

PubMed: 31264792

Applications

WB

Reactivity

Human

Sun, Jiandong et al. Icariin protects mouse Leydig cell testosterone synthesis from the adverse effects of di(2-ethylhexyl) phthalate Toxicol. Appl. Pharmacol., 114612 (2019)

PubMed: 31175881