Histatin 3 (H3)

SKU: orb2694105

Description

Histatin-3 , a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM.

Key Properties

• Target: Bacterial
• CAS Number: 112844-49-2
• MW: 4062.44
• Purity: ≥95%
• Formula: C₁₇₈H₂₅₈N₆₄O₄₈
• Protein Sequence: DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN

Storage & Handling

• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Bacterial