EGF-R (661-681) T669 Peptide

SKU: orb1980971

Description

This peptide substrate, corresponding to residues 661-681 of EGF-R with a phosphorylatable threonine at position 669, is designed for monitoring MAPK (ERK1/2) enzymatic activity. It is widely used in in vitro kinase assays for biochemical research and drug discovery efforts targeting the MAPK signaling pathway.

Research Area

Cancer Biology, Signal Transduction

Key Properties

• Target: p38 MAPK
• CAS Number: 137348-21-1
• MW: 2318.63
• Formula: C₁₀₁H₁₇₂N₃₀O₃₂
• SMILES: CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131847407