Dynorphin A (1-10) (TFA)

SKU: orb1981473

Description

Dynorphin A (1-10) TFA is an endogenous opioid peptide that acts as a κ-opioid receptor agonist, binding specifically to the receptor's second extracellular loop. It functions as a non-competitive NMDA receptor antagonist, inhibiting NMDA-activated currents with an IC₅₀ of 42 µM. This peptide is a valuable research tool for studying neuropathic pain, addiction, and neuroprotection in both cellular and animal models.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: Opioid Receptor
• MW: 1348.48
• Purity: 98.18% (May vary between batches)
• Formula: C₅₉H₉₂F₃N₁₉O₁₄
• SMILES: [H]N[C@@H](CC1=CC=C(C=C1)O)C(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([H])(C(N[C@H](C(N3CCC[C@H]3C(O)=O)=O)CCCNC(N)=N)=O)[C@@H](C)CC)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)=O)=O.O=C(C(F)(F)F)O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Opioid Receptor