DMAP1 (C) Antibody, Rabbit Polyclonal

SKU: orb67071

Description

Rabbit polyclonal to DMAP1.DNA methyltransferase 1-associated protein 1 (DMAP1) is a subunit of several distinct complexesinvolved in the repression or activation of transcription. DMAP1 can independently represstranscription and is targeted to replication foci throughout S phase by interacting directly with the Nterminusof DNA methyltransferase 1 (DNMT1). During late S phase, histone deacetylase 2 (HDAC2)is added to this complex, providing a means to deacetylate histones in transcriptionally inactiveheterochromatin following replication. DMAP1 is also a component of the nucleosomeacetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibilitygene 101 and the pro-apoptotic death-associated protein 6, among others.

Research Area

Epigenetics & Chromatin

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human DMAP1
• Molecular Weight: 53
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-DMAP1 antibody,anti-DNA methyltransferase 1associated protein 1 antibody,anti-DNMAP1 antibody,anti-DNMT1associated protein 1 antibody,anti-KIAA1425 antibody

Quick Database Links

UniProt

Q9NPF5