[D-p-Cl-Phe6,Leu17]-VIP

SKU: orb1679251

Description

This compound is a selective vasoactive intestinal peptide (VIP) receptor antagonist with an IC50 of 125.8 nM, showing no significant activity on glucagon, secretin, or GRF receptors. It is a valuable research tool for investigating VIP-mediated signaling in neurobiology, immunology, and circadian rhythm studies using both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: PACAP
• CAS Number: 102805-45-8
• MW: 3342.24
• Formula: C₁₄₈H₂₃₉ClN₄₄O₄₂
• SMILES: [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](CC3=CC=C(Cl)C=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)N)=O)CO)=O)CC(O)=O)=O)C)=O)C(C)C)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCCN)=O)CCC(N)=O)=O)CC(C)C)=O)C)=O)C(C)C)=O)CCCCN)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(N)=O)=O)CC(C)C)=O)[C@H](CC)C)=O)CO)=O)CC(N)=O)=O)CC(C)C)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131843215