Calmodulin-Dependent Protein Kinase II (281-309)

SKU: orb1983835

Description

This synthetic peptide corresponds to residues 281-309 of CaM Kinase II and is phosphorylatable at Thr286 by PKC. Its phosphorylation potently inhibits CaM Kinase II activity with an IC50 of 80 nM, making it a valuable tool for studying kinase regulation and signaling pathways in both cellular and biochemical assays.

Research Area

Neuroscience, Signal Transduction

Key Properties

• Target: CaMK
• CAS Number: 116826-37-0
• MW: 3374.06
• Formula: C₁₄₆H₂₅₄N₄₆O₃₉S₃
• SMILES: [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@H](CCSC)N)=O)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)[C@@H](C)C)=O)CC(O)=O)=O)CS)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CC(C)C)=O)CCSC)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC(C)C)=O)[C@H](CC)C)=O)C)=O)=O)CCCCN)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C)=O)CC(N)=O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172653429