AVS Bio - TFPI-Alpha-(His)C, Human, Recombinant

SKU: T005

Description

This protein is a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI-alpha inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Alternative splicing of the mRNA results codes for TFPI-1-beta, which is a shorter form of the protein and contains a PGI-anchor.

Storage & Handling

• Storage: -80°C
• Form/Appearance: solution
• Expiration Date: 6 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only