Apelin-13 [Pyr1] peptide

SKU: orb233903

Description

Apelin-13 [Pyr1] peptide

Images & Validation

• Application Notes:
  The pyroglutamyl form of apelin-13 exhibited a high activity with an EC₅₀ value of 0.30 nM. pERPRLSHKGPMPF is probably the final product of the post-translational modification of apelin and the biologically active endogenous ligand. [Pyr1]-Apelin-13 has been identified as the predominant apelin isoform in the human heart. Pyr-Apelin-13 stimulates glucose utilization in normal and obese insulin-resistant mice. It could be required for the maintenance of insulin sensitivity.

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Key Properties

• Source: Synthetic
• CAS Number: 217082-60-5
• MW: 1533.85
• Purity: > 95%
• Formula: C₆₉H₁₀₈N₂₂O₁₆S
• Protein Sequence: Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

Storage & Handling

• Storage: Shipped at 4°C. Store at -20°C for one year.
• Form/Appearance: Lyophilized powder
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only