Presenilin 1 Mouse Polyclonal Antibody

• Catalog Number: orb11308
• Category: Antibodies
• Description: Presenilin 1 Mouse Polyclonal Antibody
• Species/Host: Mouse
• Clonality: Polyclonal
• Tested applications: IF, IHC-Fr, IHC-P
• Predicted Reactivity: Bovine, Canine, Equine, Gallus, Porcine, Rabbit, Rat
• Reactivity: Human, Mouse
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human presenilin 1 (10-80/467aa)
• Antibody Type: Primary Antibody
• Concentration: 1mg/ml
• Dilution range: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
• Form/Appearance: Liquid
• Conjugation: Unconjugated
• MW: 34/52 kDa
• Target: PSEN1
• UniProt ID: P49768
• RRID: AB_10752369
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Alternative names: Presenilin-1 NTF subunit; AD 3; AD3; Ad3h; Alzheim
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

Xuemei Liu 1 2, Ai Luo 1, Mei Yang 1 3, Jian Luo 4, Huifang Li 5, Xiaoting Chen 6, Bing Mao 1, Hongli Jiang 7, Wei Liu Baicalin restores innate lymphoid immune imbalance during exacerbation of COPD Immunol Res, (2025)

PubMed: 40234295

Applications

IF

Reactivity

Mouse

Paraformaldehyde-fixed, paraffin embedded (mouse liver tissue), Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30 min, Antibody incubation with (presenilin 1) Monoclonal Antibody, Unconjugated (orb11308) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Mouse) instructionsand DAB staining.