Presenilin 1 Mouse Polyclonal Antibody

SKU: orb11308

Description

Presenilin 1 Mouse Polyclonal Antibody

Research Area

Autophagy, Cell Biology, Cell Cycle, Metabolism, Neuroscience, Notch Signaling Pathway, Protease, Signal Transduction

Images & Validation

• Tested Applications: IF, IHC-Fr, IHC-P
• Dilution range: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
• Reactivity: Mouse
• Predicted Reactivity: Bovine, Canine, Equine, Gallus, Human, Porcine, Rabbit, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human presenilin 1 (10-80/467aa)
• Target: PSEN1
• Molecular Weight: 34/52 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Disclaimer: For research use only

Alternative Names

Presenilin-1 NTF subunit; AD 3; AD3; Ad3h; Alzheimer Disease 3; EC 3.4.23.; FAD; Homo Sapiens Clone CC44 Senilin 1; Presenilin 1 Alzheimer disease 3; Presenilin 1; Presenilin-1 CTF12; Presenilin1; Protein S182; PS 1; PS-1; PS1; PS1-CTF12; PSEN 1; PSEN1; PSN 1; PSN1; PSN1_HUMAN; PSNL 1; PSNL1; S182; S182 Protein; Senilin 1; Senilin1.

Paraformaldehyde-fixed, paraffin embedded (mouse liver tissue), Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30 min, Antibody incubation with (presenilin 1) Monoclonal Antibody, Unconjugated (orb11308) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Mouse) instructionsand DAB staining.

Quick Database Links

Gene Symbol

PSEN1

UniProt

P49768

References

Xuemei Liu 1 2, Ai Luo 1, Mei Yang 1 3, Jian Luo 4, Huifang Li 5, Xiaoting Chen 6, Bing Mao 1, Hongli Jiang 7, Wei Liu Baicalin restores innate lymphoid immune imbalance during exacerbation of COPD Immunol Res, (2025)

PubMed: 40234295

Applications

IF

Reactivity

Mouse