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Catalog Number | orb1961623 |
---|---|
Category | Proteins |
Description | Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome. |
Tag | N-6xHis |
Purity | 98.00% |
MW | 24 KDa (reducing condition) |
UniProt ID | O43447 |
Protein Sequence | Met1-Met177 |
Expression System | E. coli |
Biological Origin | Human |
Biological Activity | Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome. |
Expression Region | Met1-Met177 |
Storage | -20°C |
Note | For research use only |
Application notes | 0 |
Expiration Date | 6 months from date of receipt. |
Greater than 95.0% as determined by SDS-PAGE. | |
Escherichia Coli |
≥90% as determined by SDS-PAGE | |
This protein contains the human PPIH(Met1-Met177) was fused with the N-terminal His Tag and expressed in E. coli. |