PML (C) Antibody, Rabbit Polyclonal

SKU: orb131859

Description

Rabbit polyclonal to PML. Protein PML functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. PML acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMOmediated modifications and interactions.

Research Area

Apoptotic, Cancer, Epigenetics, Immunology, Infectious Diseases, Neuroscience, Signaling Pathways

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:3000
• Reactivity: Human
• Application Notes:
  WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human PML.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human PML
• Molecular Weight: 98
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti Protein PML antibody, anti Promyelocytic leukemia protein antibody, anti RING finger protein 71 antibody, anti Tripartite motif-containing protein 19 antibody, anti MYL antibody, anti PP8675 antibody, anti RNF71 antibody, anti TRIM19 antibody

Quick Database Links

UniProt

P29590