Phospho-mTOR (Ser2448) Antibody

• Catalog Number: orb1733081
• Category: Antibodies
• Description: An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: IHC, WB
• Reactivity: Human, Mouse
• Isotype: Rabbit IgG
• Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 289 kDa; Observed MW: 289 kDa
• Entrez: 2475
• UniProt ID: P42345
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/thr
• Note: For research use only
• Expiration Date: 12 months from date of receipt.