Phospho-Mre11 (Ser678) Rabbit Polyclonal Antibody

SKU: orb185227

Description

Phospho-Mre11 (Ser678) Rabbit Polyclonal Antibody

Research Area

DNA Repair, DNA and RNA, DNA and RNA Research, DNA and RNA Researchh, Homelogous Recombination, Telomeres

Images & Validation

• Tested Applications: ELISA, ICC, IF, IHC-Fr, IHC-P
• Dilution range: IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000
• Reactivity: Human
• Predicted Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthesised phosphopeptide derived from human Mre11 around the phosphorylation site of Ser678 SQ(p-S)QV
• Target: MRE11
• Molecular Weight: 81 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Disclaimer: For research use only

Alternative Names

Mre11(phospho S678); p-Mre11(phospho S678); AT like disease; Ataxia telangiectasia disorder like; ATLD; DNA recombination and repair protein; Double strand break repair protein MRE11A; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; meiotic recombination(S. cerevisiae) 11 homolog A; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A(S. cerevisiae); Meiotic recombination 11 homolog A; MmMRE11A; Mre 11; MRE 11a; MRE 11b; MRE11 homolog 1; MRE11 homolog A; MRE11 meiotic recombination 11 homolog A(S. cerevisiae); MRE11 meiotic recombination 11 homolog A; MRE11_HUMAN; MRE11A; MRE11b; OTTHUMP00000236830; OTTHUMP00000236831; OTTHUMP00000236832; OTTHUMP00000236833.

Quick Database Links

Gene Symbol

MRE11

UniProt

P49959

References

Yuping Chen 1, Jinhuan Wu 1, Linhui Zhai 2, Tingting Zhang 3, Hui Yin 4, Huanyao Gao 5, Fei Zhao 6, Zhe Wang 1, Xiaoning Yang 7, Mingpeng Jin 1, Bingsong Huang 1, Xin Ding 1, Rui Li 1, Jie Yang 8, Yiming He 1, Qianwen Wang 1, Weibin Wang 9, Jake A Kloeber 10, Yunxuan Li 3, Bingbing Hao 2, Yuanyuan Zhang 11, Jiadong Wang 9, Minjia Tan 2, Ke Li 3, Ping Wang 12, Zhenkun Lou 13, Jian Yuan Metabolic regulation of homologous recombination repair by MRE11 lactylation Cell, (2024)

PubMed: 38128537