Phospho-IRF3 (Ser386) Rabbit Polyclonal Antibody

SKU: orb1860

Description

Phospho-IRF3 (Ser386) Rabbit Polyclonal Antibody

Research Area

Infectious Disease & Virology

Images & Validation

• Tested Applications: FC, IF, IHC-Fr, IHC-P, WB
• Dilution Range: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1ug/test
• Reactivity: Human, Mouse
• Predicted Reactivity: Bovine, Canine, Porcine, Rabbit, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthesised phosphopeptide derived from human IRF3 around the phosphorylation site of Ser386 S(p-S)LE
• Target: IRF3
• Molecular Weight: 47 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IIAE7; C920001K05Rik; IRF-3; IRF3_HUMAN; IRF3; IRF3_MOUSE; interferon regulatory factor 3; IRF3 (phospho-S386); p-IRF3; phospho-IRF3; IRF3 (phospho-Ser386)

Quick Database Links

Gene Symbol

IRF3

UniProt

Q14653

I C Salaroglio 1, P Aviles 2, J Kopecka 1, A Merlini 3, F Napoli 4, L Righi 4, S Novello 3, H Sullivan 2, C Cuevas 2, G V Scagliotti # 5, C Riganti Ecteinascidin synthetic analogues: a new class of selective inhibitors of transcription, exerting immunogenic cell death in refractory malignant pleural mesothelioma J Exp Clin Cancer Res, (2024)

PubMed: 39709435

Massimiliano G. Bianchi, Manfredi Allegri, Martina Chiu, Anna L. Costa, Magda Blosi, Simona Ortelli, Ovidio Bussolati, Enrico Bergamaschi Lipopolysaccharide Adsorbed to the Bio-Corona of TiO2 Nanoparticles Powerfully Activates Selected Pro-inflammatory Transduction Pathways Frontiers in Immunology, 8, (2017)

PubMed: 28824614

Applications

WB

Reactivity

Mouse