Phospho-IRE1a (Ser 726) Rabbit Polyclonal Antibody

SKU: orb157704

Description

Phospho-IRE1a (Ser 726) Rabbit Polyclonal Antibody

Research Area

Cell Biology

Images & Validation

• Tested Applications: FC, IF, IHC-Fr, IHC-P
• Dilution Range: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1ug/test
• Reactivity: Human, Rat
• Predicted Reactivity: Bovine, Canine, Equine, Mouse, Porcine, Rabbit

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthesised phosphopeptide derived from human IRE1a around the phosphorylation site of Ser726 SF(p-S)RR
• Target: ERN1
• Molecular Weight: 107 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IRE1-BETA; IRE1b; IRE2p; hIRE2p; Ern1; Ire1; mIre1; ERN1_HUMAN; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1 (hIRE1p); Ire1-alpha (IRE1a); ERN1_MOUSE; Inositol-requiring protein 1; endoplasmic reticulum to nucleus signaling 1; ER to nucleus signalling 1; inositol-requiring enzyme 1; Serine/threonine-protein kinase/endoribonuclease IRE1; ERN1 | IRE1a (phospho-S726); p-IRE1a; phospho-IRE1a; p-ERN1; ERN1 | IRE1a (phospho-Ser726)

Quick Database Links

Gene Symbol

ERN1

UniProt

O75460

Mustafa Oztatlici,1 Hulya Oztatlici,2 Suna Karadeniz Saygili,3 Kaya Kaya,4 and Ilker Deniz Cingoz4 Cyclophosphamide stimulates endoplasmic reticulum stress and induces apoptotic cell death in human glioblastoma cell lines Rom J Morphol Embryol, (2024)

PubMed: 38527981

Applications

IHC

Reactivity

Human

Suna Karadeniz Saygili et al. The effect of salubrinal on the endoplasmic reticulum stress pathway in heat-stressed spermatogonial cells in vitro FEBS Open Bio, (2025)

PubMed: 41316514

Applications

IF

Reactivity

Mouse