Phospho-Insulin Receptor Beta (Tyr1185) Rabbit Polyclonal Antibody

SKU: orb5550

Description

Phospho-Insulin Receptor Beta (Tyr1185) Rabbit Polyclonal Antibody

Research Area

Metabolism Research

Images & Validation

• Tested Applications: ELISA
• Dilution Range: ELISA=1:5000-10000
• Reactivity: Human
• Predicted Reactivity: Bovine, Canine, Gallus, Mouse, Porcine, Rabbit, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Insulin Receptor Beta around the phosphorylation site of Tyr1185 DI(p-Y)ET
• Target: INSR
• Molecular Weight: 68/152 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CD220; HHF5; 4932439J01Rik; D630014A15Rik; IR; IR-A; IR-B; INSR_HUMAN; INSR; 2.7.10.1; INSR_MOUSE; INSR_RAT; insulin receptor; INSR | INSR beta (phospho-Y1185); p-INSR beta; phospho-INSR beta; p-IR; INSR | INSR beta (phospho-Tyr1185)

Quick Database Links

Gene Symbol

INSR

UniProt

P06213

Rudar, Marko et al. Prematurity blunts protein synthesis in skeletal muscle independently of body weight in neonatal pigs Pediatr Res, (2023)

PubMed: 36627358

Jane K Naberhuis, Agus Suryawan, Hanh V Nguyen, Adriana Hernandez-Garcia, Stephanie M Cruz, Patricio E Lau, Oluyinka O Olutoye, Barbara Stoll, Douglas G Burrin, Marta L Fiorotto, Teresa A Davis Prematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets AJP Endocrinology and Metabolism, 317, E839 (2019)

PubMed: 31503514

Applications

WB

Reactivity

Porcine