Phospho-BACE1 (Ser498) Rabbit Polyclonal Antibody

SKU: orb182445

Description

Phospho-BACE1 (Ser498) Rabbit Polyclonal Antibody

Images & Validation

• Tested Applications: IF, IHC-Fr, IHC-P
• Dilution range: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
• Reactivity: Human, Mouse, Rat
• Predicted Reactivity: Bovine, Canine, Equine, Gallus, Porcine, Rabbit

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated Synthesised phosphopeptide derived from human BACE1 around the phosphorylation site of Ser498 DI(p-S)LL
• Target: BACE1
• Molecular Weight: 51 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Disclaimer: For research use only

Alternative Names

BACE1(phospho-Ser498); BACE1(phospho-S498); p-BACE1(Ser498); p-BACE1(Se498); APP beta secretase; Asp 2; ASP2; Aspartyl protease 2; BACE 1; BACE; beta secretase 1; beta secretase; beta site amyloid beta A4 precursor protein cleaving enzyme; beta site amyloid precursor protein cleaving enzyme 1; beta site amyloid precursor protein cleaving enzyme; beta site APP cleaving enzyme 1; beta site APP cleaving enzyme; FLJ90568; HSPC104; KIAA1149; Memapsin-2; Memapsin 2; Memapsin2; Membrane associated aspartic protease 2; Transmembrane aspartic proteinase Asp2; BACE1_HUMAN; beta-secretase 1; beta-site amyloid precursor protein cleaving enzyme 1; beta-site APP cleaving enzyme 1; Membrane-associated aspartic protease 2.

Paraformaldehyde-fixed, paraffin embedded (Mouse brain), Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30 min, Antibody incubation with (phospho-BACE1 (Ser498)) Polyclonal Antibody, Unconjugated (orb182445) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.

Quick Database Links

Gene Symbol

BACE1

UniProt

P56817