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Catalog Number | orb341528 |
---|---|
Category | Small Molecules |
Description | PF-04979064 is a highly potent and orally bioavailable PI3K/mTOR dual inhibitor developed through structure-based drug design. It inhibited mTOR, PI3Kα, β, δ and γ isoforms and AKT phosphorylation with IC50 as 2.64 nM, 0.395 nM, 0.111 nM, 0.122 nM and 28. |
CAS Number | [1220699-06-8] |
MW | 446.5 |
SMILES | C[C@@H](C(N1CCC(N2C(=O)N(C)C3=CN=C4C=CC(C5C=CC(C)=NC=5)=NC4=C23)CC1)=O)O |
Formula | C24H26N6O3 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1220699-06-8 |
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