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Description
Research Area
Neuroscience
Images & Validation
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Key Properties
−| Source | E. coli |
|---|---|
| Biological Activity | Human Persephin induces RET phosphorylation using a concentration range of 0.1 - 1.0 ng/mL. Human Persephin binds to mammalian GFRa4 with the Kd of 100pM. Other members of the GDNF family (Artemin, GDNF and Neurturin) do not bind to mammalian GFRa4. |
| Target | PSPN |
| Purity | Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
| Protein Sequence | ALSGPCQLWS LTLSVAELGL GYASEEKVIF RYCAGSCPRG ARTQHGLALA RLQGQGRAHG GPCCRPTRYT DVAFLDDRHR WQRLPQLSAA ACGCGG |
Storage & Handling
−| Storage | The lyophilized Persephin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Persephin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Persephin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
|---|---|
| Form/Appearance | Lyophilized |
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−PSP, Persephin, PSP
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Quick Database Links
UniProt Details
− No UniProt data available
NCBI Reference Sequences
−Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product| Protein | NP_004149.1 |
|---|
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Protocol Information
Protein Handling and Storage Guide
Protein Handling Guide
Persephin Recombinant Protein (orb1230613)
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