PD-L2 antibody

• Catalog Number: orb613948
• Category: Antibodies
• Description: Rabbit monoclonal antibody to PD-L2
• Species/Host: Rat
• Clonality: Monoclonal
• Clone Number: TY25
• Tested applications: Blocking, FC, IP, WB
• Reactivity: Mouse
• Isotype: IgG
• Immunogen: This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: PD-L2
• UniProt ID: Q9WUL5
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: CD273; B7-DC; PDL2; B7DC; programmed death ligand
• Note: For research use only
• Application notes: This antibody has been used to detect murine PD-L2 by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling.
• Expiration Date: 12 months from date of receipt.