PACS-1 Antibody

SKU: orb248132

Description

PACS proteins are involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. PACS-1, or Phosphofurin acidic cluster sorting protein 1, is involved in protein sorting and ion channel trafficking. It directs the trans-Golgi network (TGN) localization of furin and M6PR (Mannose 6-phosphate receptor). PACS-1 also mediates the binding of VAMP4, a TGN-to-endosome transport protein, to AP-1.

Images & Validation

• Tested Applications: WB
• Dilution range: Western blot: 1-3ug/ml
• Reactivity: Human, Mouse
• Application Notes:
  Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: A recombinant protein fragment from the intermal portion of human PACS-1 was used as the immunogen for this antibody.
• Purification: Protein A affinity chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 1X PBS, pH 7.4
• Disclaimer: For research use only

Western blot testing of human samples with PACS-1 antibody at 1 ug/ml.