OGN/Osteoglycin Protein, Human, Recombinant (His)

• Catalog Number: orb1954871
• Category: Small Molecules
• Description: OGN/Osteoglycin Protein, Human, Recombinant (His)
• Purity: 98.00%
• MW: Approxiamtely 33.2 kDa
• Biological Activity: OGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor-beta and may regulate osteoblast differentiation. OGN is broadly expressed in the gall bladder, endometrium, and other tissues. OGN reduced Zeb-1 expression via EGFR/Akt leading to inhibition of epithelial-mesenchymal transition. In vitro and in vivo, the OGN expression was demonstrated to reduce cell proliferation, inhibit invasion of colon cancer cells then impede cancer progression. Diseases associated with OGN include Inhibited Male Orgasm and Cornea Plana.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.