NSMase Rabbit Polyclonal Antibody

SKU: orb312318

Description

NSMase Rabbit Polyclonal Antibody

Research Area

Alzheimer's Disease, Neuroscience, Oligodendrocyte Marker

Images & Validation

• Tested Applications: WB
• Dilution Range: WB=1:500-2000
• Reactivity: Human
• Predicted Reactivity: Bovine, Equine, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human nSMase (1-100/423aa)
• Target: SMPD2
• Molecular Weight: 47 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ISC1; Lyso platelet activating factor phospholipase C; Lyso-PAF-PLC; Lyso-platelet-activating factor-phospholipase C; N-SMase; Neutral sphingomyelinase; NSMA_HUMAN; nSMase; NSMASE1; Smpd2; Sphingomyelin phosphodiesterase 2; Sphingomyelin phosphodiesterase 2, neutral membrane(neutral sphingomyelinase).

Sample: MOLT-4 (Human) Cell Lysate at 30 ug, Primary: Anti-nSMase (orb312318) at 1/500 dilution, Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution, Predicted band size: 47 kD, Observed band size: 47 kD.

Quick Database Links

Gene Symbol

SMPD2

UniProt

O60906

Patrycja Bielawiec 1, Lara Swierkot 2, Karolina Konstantynowicz-Nowicka 2, Adrian Chabowski 2, Agnieszka Błachnio-Zabielska 3, Ewa Harasim-Symbor Cannabigerol - A potent regulator of insulin sensitivity in rat's skeletal muscle via targeting the sphingolipid metabolism and PI3K/Akt/mTOR pathway? Int J Biochem Cell Biol, (2025)

PubMed: 40482851

Applications

WB

Reactivity

Rat