Nonapeptide-1

• Catalog Number: orb1910621
• Category: Small Molecules
• Description: Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC50: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer.
• CAS Number: [158563-45-2]
• MW: 1206.50359177589
• SMILES: S(C)CC[C@@H](C(N1CCCC1C(N[C@@H](C(NC(C(NC(CC1=CNC2C=CC=CC1=2)C(NC(CC1C=CC=CC=1)C(N[C@@H](CCCCN)C(N1CCC[C@H]1C(NC(C(N)=O)C(C)C)=O)=O)=O)=O)=O)CCC/N=C(\N)/N)=O)CC1C=CC=CC=1)=O)=O)N
• Formula: C₆₁H₈₇N₁₅O₉S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.