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Catalog Number | orb1960997 |
---|---|
Category | Proteins |
Description | Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one of the sarcomeric proteins and plays an important role in myofibrillogenesis and the modulation of calcineurin signaling. It may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and plays an important role in the modulation of calcineurin signaling. Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder. |
Tag | C-6xHis |
Protein Sequence | Met1-Leu264 |
UniProt ID | Q9NPC6 |
MW | 38 KDa (reducing condition) |
Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Expression System | E. coli |
Biological Origin | Human |
Expression Region | Met1-Leu264 |
Storage | -20°C |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human MYOZ2(Met1-Leu264) was fused with the C-terminal His Tag and expressed in E. coli. |
60.8 kDa (predicted); 60 kDa (reducing conditions) |