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Murine Cardiotrophin-1 protein
Catalog Number: orb107700
| Catalog Number | orb107700 |
|---|---|
| Category | Proteins |
| Description | Cardiotrophin1(CT1)is a member of the cytokine family which also includes IL-6, IL-11, leukemia inhibitory factor (LIF),oncostatin M (OSM), and ciliary neurotrophic factor (CNTF). CT-1 is a pleiotropic cytokine which is expressed in various tissuesincluding the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung. In addition, CT-1 which induces cardiac myocytehypertrophy in vitro can bind to and activate the ILST/gp130 receptor. Murine CT1encodes a 203 amino acid (a.a.) residueprotein that lacks a hydrophobic signal peptide. Human and murine CT1share 80 % a.a. sequence identity and exhibit crossspeciesactivity. |
| Target | Cardiotrophin-1 |
| Conjugation | Unconjugated |
| Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, 300 mM NaCl, 3 mM beta -mercaptoethanol, pH 8.5 |
| Purity | > 95 % by SDS-PAGE and HPLC analyses |
| Protein Sequence | LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDAATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKILDDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL |
| MW | 18.2 kDa |
| Tested applications | HPLC, SDS-PAGE |
| Biological Origin | E.coli |
| Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Alternative names | Murine Cardiotrophin1 protein |
| Note | For research use only |
SDS-PAGE analysis of Murine Cardiotrophin-1 protein
