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MUC5AC Antibody

Catalog Number: orb639823

DispatchUsually dispatched within 5-10 working days
$ 410.00
Catalog Numberorb639823
CategoryAntibodies
DescriptionThis MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Species/HostMouse
ClonalityRecombinant
Clone NumberrMUC5AC/3779
Tested applicationsIHC-P
ReactivityHuman
IsotypeMouse IgG1, kappa
ImmunogenAn M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient was used as the immunogen for this recombinant MUC5AC antibody.
Antibody TypePrimary Antibody
Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml
PurityProtein G affinity chromatography
ConjugationUnconjugated
Formula0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Hazard InformationThis recombinant MUC5AC antibody is available for research use only.
UniProt IDP98088
StorageStore the recombinant MUC5°C antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Buffer/Preservatives0.2 mg/ml with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
NoteFor research use only
Application notesOptimal dilution of the antibody should be determined by the researcher.
Expiration Date12 months from date of receipt.
MUC5AC Antibody

IHC staining of FFPE human colon with recombinant MUC5AC antibody (clone rMUC5AC/3779). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

MUC5AC Antibody

SDS-PAGE analysis of purified, BSA-free recombinant MUC5AC antibody (clone rMUC5AC/3779) as confirmation of integrity and purity.

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