Mouse Transferrin R2 Protein

• Catalog Number: orb348801
• Category: Proteins
• Description: Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
• Reactivity: Mouse
• Tag: N-mFc(mIgG1)
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 101.1 kDa
• Target: Transferrin R2
• Protein Sequence: NP_056614.3
• Source: Mouse TFR2, Mouse Fc Tag (orb348801) is expressed from human 293 cells (HEK293). It contains AA Arg 103 - Phe 798 (Accession # Q9JKX3-1).
• Expression System: HEK293
• Expression Region: Arg 103 - Phe 798
• Endotoxins: 0.1 EU per μg
• NCBI: NP_056614.3
• Storage: -20℃
• Buffer/Preservatives: Tris with Glycine, Arginine and NaCl, pH7.5
• Alternative names: Transferrin R2,TFR2
• Note: For research use only
• Application notes: This protein carries a mouse IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 101.1 kDa. The protein migrates as 116 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Mouse Transferrin R2 protein