Mouse Glypican 3 Protein

• Catalog Number: orb55829
• Category: Proteins
• Description: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
• Reactivity: Mouse
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 38.0 kDa and 24.4 kDa
• Target: Glypican 3
• Protein Sequence: NP_057906.2
• Source: Mouse Glypican 3, His Tag (orb55829) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Met 557 (Accession # Q8CFZ4-1).
• Expression System: HEK293
• Expression Region: Gln 25 - Met 557
• Endotoxins: 1.0 EU per μg
• NCBI: NP_057906.2
• Storage: -20°C
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: GPC3,OCI5,Glypican-3,GTR2-2,MXR7,DGSX,SDYS ,SGB,SG
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. This protein contains a furin-like convertase cleavage site, 354-RQYR-357, and will be partially processed into N and C-terminal fragment with calculated MW of 38.0 kDa and 24.4 kDa respectively. The protein migrates as 38-40 kDa and 62-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.