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Catalog Number | orb18126 |
---|---|
Category | Proteins |
Description | Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. |
Reactivity | Mouse |
Tag | C-Fc |
Form/Appearance | Powder |
Purity | 90% |
Conjugation | Unconjugated |
MW | 38.0 kDa and 49.1 kDa |
Target | Glypican 3 |
Protein Sequence | NP_057906 |
Source | Mouse Glypican 3, Fc Tag (orb18126) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Met 557 (Accession # Q8CFZ4-1). |
Expression System | HEK293 |
Expression Region | Gln 25 - Met 557 |
Endotoxins | 1.0 EU per μg |
NCBI | NP_057906 |
Storage | -20℃ |
Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
Alternative names | GPC3,OCI5,Glypican-3,GTR2-2,MXR7,DGSX,SDYS ,SGB,SG Read more... |
Note | For research use only |
Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. This protein contains a furin-like convertase cleavage site, 354-RQYR-357, and will be partially processed into N and C-terminal fragment with calculated MW of 38.0 kDa and 49.1 kDa respectively. The protein migrates as 40 kDa, 60 kDa and 100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Mouse Glypican 3 protein
Unconjugated | |
95% | |
38.0 kDa and 24.4 kDa | |
Mouse Glypican 3, His Tag (orb55829) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Met 557 (Accession # Q8CFZ4-1). |
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