Mouse Ac-[Cys (Acm)-EGF amide peptide

SKU: orb233852

Description

Mouse Ac-[Cys (Acm)-EGF amide peptide

Research Area

Cancer Biology

Images & Validation

• Application Notes:
  This EGF-derived peptide is known as a laminin antagonist. It blocks the stimulatory effects of laminin in cell motility and chick angiogenesis. This peptide binds to a breast cancer- and endothelial cell-associated receptor, which is specific for residues 925 to 933 of the laminin B1 chain. The IC₅₀ values for displacement of laminin are in the range of 1-3 nM, depending on the cells. This peptide has an antimetastatic potential.

Key Properties

• Source: Synthetic
• CAS Number: 122053-92-3
• MW: 1255.45
• Purity: > 95%
• Formula: C₅₁H₈₂N₁₆O₁₇S₂
• Protein Sequence: Ac-Cys(Acm)-Val-Ile-Gly-Tyr-Ser-Gly-Asp-Arg-Cys(Acm)-NH2

Storage & Handling

• Storage: Shipped at 4°C. Store at -20°C for one year.
• Form/Appearance: Lyophilized powder
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of orb233852.